Asymmetric aldol reaction of aldehyde and Evans chiral auxiliary (acyl oxazlidineone).
Highly enantioselective aldol condensation of the chiral N-acyl-oxazolidone via its dibutylboryl enolate with the appropriate aldehyde:
D. A. Evans et al.,J. Am. Chem. Soc.101, 6120 (1979); 103, 2127 (1981).
D. A. Evans et al.,J. Am. Chem. Soc.103, 2127 (1981).
Mechanistic studies:
D. A. Evans et al., J. Am. Chem. Soc. 103, 3099 (1981).
Review: